10. If a person expressed mutated genes or lost the enzymes used for rearrangement of heavy chain and light chain genes what might happen to that person? What cells would be affected? How would the person be affected as a whole? (2pts)

11. What is the purpose and function of MHC I and MHC II molecules? (2pts)

12. One of the characteristic features of the MHC receptors is the large number of different alleles at each gene locus encoding for the receptor.

a. Where are most of the polymorphic amino acid residues located in MHC molecules? What is the significance of this location? (2pts)

b. What are some of the mechanisms that result in the MHC polymorphism we see in individuals? (2pts)

13. What is the purpose of class I MHC molecules? What cells display these molecules? Where do the antigens they display come from? (3pts)

14. What is the purpose of class II MHC molecules? What cells display these molecules? Where do the antigens they display come from? (3pts)

15. What kind of proteins are considered class III MHC molecules? What role in immunity do they play? (2pts)

16. What are professional APCs? Name some examples of professional APCs. (2pts)

17. Give an example of a nonprofessional APC. When can these cells function in antigen presentation? (2pts)

18. A process called antigen cross-presentation happens in dendritic cells only. Explain what cross-presentation is (4pts)

19. Molecules of the CD1 family have been shown to present non-peptide antigens. What types of antigens do they present? (2pts)

6. Diabetic Ketoacidosis can occur in a patient with severely uncontrolled diabetes. Which of the following is a key contributor to the acidosis?

a. uncontrolled gluconeogenesis during the absorptive and post-absorptive state

b. Increased liver glycogenesis during the absorptive state

c.Decreased ketone body production in the liver during the post-absorptive state

7. Which of the following statements regarding Type 1 diabetics is true?

a. Type 1 debiatics cannot produce insulin

b. Type 1 diabetics are typically treated with insulin sensitizers

c. Type 1 diabetics are insulin resistant

8. Identify the gluconeogenic pathway

a. Glycogen--- glucose

b. Fatty acid--- keto acid----glucose

c. Amino acid--- keto acid----- glucose

9. Which of the following would you expect to be associated with this presentation?

Patient- 21 year old male

Chief complaint- Abdominal pain, nausea and vomiting. increased thirst and frequency of urination

Background- Patient is a type 1-diabetic

Examination notes- Insulin pump appears to have stopped working, elevated plasma glucose levels following a finger prick.

a. Decreased serum ketones

b. increased Plasma pH

c. Increased protein glycation (AGEs) within the plasma

10. Which of the following events is most likely occurring during the postabsorptive state?

a. Glycogen is being hydrolyzed releasing individual glucose monomers into the blood

b. chylomicrons are circulating in the plasma

c. Gluconeogenesis is actively occurring in must cells within the body

What is the task of rational choice theory? a. to identify the feelings and emotions influencing consumers' decisions b. to identify the trade offs consumers are willing to accept with respect to product attributes c. to identify or discover the one optimal choice for the decision confronting the decision maker d. to identify the cognitive structure of consumers when making a choice

If Fred plays tennis every day, but tells his wife he would rather be working longer hours at his job, economists would say which of the following about his behavior, assuming that his work hours are totally up to him. : a. Fred has a preference for tennis over work at the times he plays tennis. b. Fred prefers to work rather than to play more tennis since that is what he tells his wife. Economists are not about to question a person's motives. c. Fred is irrational because he is not doing what he says he wants to do. d. There is no way to model the behavior of someone who claims one thing and does another.

Neoclassical economic theory claims to a. describe human actions in as realistic a manner as possible. b. have tools which predict normal and abnormal behavior. c. arrive at the best available predictions by assuming that people merely act as if they constantly calculated costs and benefits of all actions. d. do all of the above.

Which statement is true of a typical market supply and demand situation? : a. At equilibrium supply equals demand and the quantity supplied equals the quantity demanded. b. At a price lower than the equilibrium price, demand has increased from where it was at equilibrium c. At a price higher than equilibrium more goods are sold because firms find it profitable to produce more. d. All of the above statements are true for a market situation.

Rationality in economics implies that: : a. people are unable to assess their own preferences. b. people follow their own interests c. people have similar, if not identical IQs. d. no one can be considered irrational.

Homo Economicus, as a model of behaviour, ... : a. focuses on personal material costs and benefits rather than other more social values. b. would be a good guide for people to follow in their relationships with others. c. is built on trust of others which is why it works in a free society where trust is important. d. includes many motives for behavior that are not usually part of economic thinking.

The law of supply implies that: : a. the supply curve slopes upward. b. firms are enticed to supply more output if the price is higher c. costs of providing goods and services rise as more output is generated. d. all of the above are true.

The term ‘empty world economics’ implies that : a. the lack of natural capital is the limiting factor in economic development b. the lack of human-made capital is the limiting factor in economic development c. the lack of human capital is the limiting factor in economic development d. all of the above

Support Department Cost Allocation Using the Step or Sequential Method

The step or sequential method requires that support departments be ranked and that the highest ranking support department be allocated first to all lower ranking support departments and the producing departments. Then the highest ranking support department is closed and the second-highest ranking support department is allocated to lower ranking support departments and the producing departments. This continues until all support department cost has been allocated to the producing departments. The sequential method takes partial  account of support department reciprocity. Reciprocity occurs when one support department uses the services of another support department. For example, Maintenance uses HR and HR may use the services of Maintenance. The sequential method does not take full account of reciprocity because lower ranking support department costs are never  allocated to higher ranking support departments.

Let's use Porter Company, as an example. Porter has two producing departments (Fabricating and Assembly) and three support departments (Maintenance, Human Resources (HR) and General Factory (GF)). Porter provided the following information on the five departments:

Porter uses the sequential method of support department cost allocation, and support departments are ranked in order of direct overhead cost (from high to low). Maintenance is allocated based on machine hours, HR on direct labor hours, and GF on the basis of square footage. The Fabricating overhead rate is based on machine hours and the Assembly overhead rate is based on direct labor hours.

Calculate the allocation ratios to five significant digits and fill them into the following table (If an amount box does not require an entry, leave it blank or enter "0".) :

Using the allocation ratios, fill in the following table to allocate support department costs to the producing departments. (Round all allocated amounts to the nearest dollar. Leave cells blank that do not require an entry.)

Notice that after allocation, zero dollars remain in the support departments and all overhead cost has been allocated to the producing departments. As a check on your work, add all direct overhead costs from the first line - it equals $610,100. Then add the totals after allocation - again, it equals $610,100.

Finally, calculate the overhead rates (rounded to the nearest cent) for Fabricating and Assembly.

Fabricating overhead rate $_______ per machine hour

Assembly overhead rate $________ per direct labor hour

Support Department Cost Allocation Using the Step or Sequential Method

The step or sequential method requires that support departments be ranked and that the highest ranking support department be allocated first to all lower ranking support departments and the producing departments. Then the highest ranking support department is closed and the second-highest ranking support department is allocated to lower ranking support departments and the producing departments. This continues until all support department cost has been allocated to the producing departments. The sequential method takes partial account of support department reciprocity. Reciprocity occurs when one support department uses the services of another support department. For example, Maintenance uses HR and HR may use the services of Maintenance. The sequential method does not take full account of reciprocity because lower ranking support department costs are never allocated to higher ranking support departments.

Let's use Porter Company, as an example. Porter has two producing departments (Fabricating and Assembly) and three support departments (Maintenance, Human Resources (HR) and General Factory (GF)). Porter provided the following information on the five departments:

Porter uses the sequential method of support department cost allocation, and support departments are ranked in order of direct overhead cost (from high to low). Maintenance is allocated based on machine hours, HR on direct labor hours, and GF on the basis of square footage. The Fabricating overhead rate is based on machine hours and the Assembly overhead rate is based on direct labor hours.

Calculate the allocation ratios to five significant digits and fill them into the following table (If an amount box does not require an entry, leave it blank or enter "0".) :

Using the allocation ratios, fill in the following table to allocate support department costs to the producing departments. (Round all allocated amounts to the nearest dollar. Leave cells blank that do not require an entry.)

Notice that after allocation, zero dollars remain in the support departments and all overhead cost has been allocated to the producing departments. As a check on your work, add all direct overhead costs from the first line - it equals $610,100. Then add the totals after allocation - again, it equals $610,100.

Finally, calculate the overhead rates (rounded to the nearest cent) for Fabricating and Assembly.

Fabricating overhead rate $ per machine hour

Assembly overhead rate $ per direct labor hour

Strategic Management: A Taiwanese story about strategy and structure Before 2000 the Taiwan-based company Acer had competing strategies. For 15 years one part of the firm had been building computers for other PC sellers who would put their own labels on the machines, while another part sold very similar computers under the company’s own brand. The latter strategy was predicated on direct sales to consumers, which had brought the firm into direct competition with companies such as Dell. However, in 2000 the firm decided to adopt a new business strategy in order to increase its global market share. Acer’s manufacturing division was made an independent company (Wistron) and this enabled a smaller and more nimble sales firm to emerge. The strategy based on direct sales was discarded and replaced with a strategy focused on selling as many low-cost laptops and netbooks as possible to consumers but via a network of partners and retailers. A new logo was adopted to reflect this new strategic direction, which had proved very successful despite the industry downturn. By 2008, Acer had replaced Hewlett-Packard as the market leader in Europe, the Middle-East, and Africa, partly as a result of Acer’s success in the booming netbook market. This strategy enabled the firm to become the world’s second largest PC vendor. However, in 2011 tensions at board level over the firm’s strategic direction culminated in the resignation of Acer’s CEO Gianfranco Lanci. The difference in opinion appears to be about whether the firm’s future lay in PC’s or mobile devices. Acting CEO J.T Wang announced that the PC would continue to be the firm’s core business. In 2009 the firm entered the smartphone market with the launch of four different smartphones and the promise of more in the pipeline. Unlike Apple, which was focused on developing one phone only, Acer’s strategy is based on targeting each of its phones at a different market segment. In march MODULE FUNDAMENTALS OF HUMAN RESOURCE MANAGEMENT TOTAL MARKS 60 MARKS 2011, Acer announced that revenue projections for the first quarter in 2011 will fall short of expectations by about 10% due to weaker demand in the PC market in the US and Europe. (Source: New York Times, 2009, Bloomberg Business Week, The Financial Times, PC Pro)

Questions Discuss the purpose of Strategic Human Resource Management for organisations today. In your discussion, identify which organisational strategies have been employed by ACER over the years, justify your answer using evidence provided in the case study and discuss how these organisational strategies affect the HR strategy. (60) You are encouraged to use at least 5 current and relevant external literary sources to support your discussion on Strategic Human Resource Management.

Entropy is

A. order

B. complexity

C. disorder

D. Both order and disorder are correct

E. Both complexity and disorder are corre

How can small molecules make their way past the cell membrane?

A. they pass through transmembrane channel proteins

B. they are hydrophobic

C. they are hydrophilic

Cell theory states that

A. life is spontaneously generated

B. New cells come only from pre-existing cells

C. cells can form from non-organic material

Animals store energy in a polymer composed of many glucose molecules called:

A. glycogen

B. cellulose

C. chitin

D. starch

A cell produces 36 ATPs per glucose, however, if you calculated the total energy in a glucose molecule, 90 ATPs should be generated. Why is this so?

A. Some of the energy is destroyed

B. Some of the energy is used to do work in the cell

C. Some energy is lost as heat

In animal cells the primary organelle that generates molecules of ATP is the

A. ribosome

B. lysosome

C. Golgi body

D. mitochondrion

What is osmosis?

A. entry of water into cells through transmembrane channel proteins

B. formation of ATP

C. asorption of water through a membrane

Which organelle carries out the bulk of respiration?

A. chloroplasts

B. Golgi apparatus

C. mitochondria

The process of converting the energy from food molecules into energy of ATP is

A. cellular respiration

B. catalysis

C. thermodynamics

D. photosynthesis

bjects that are moving are said to possess:

A. kinetic energy

B. potential energy

C. entropy

D. living energy

Glycolysis

A. uses oxygen

B. does not use oxygen

C. uses carbon dioxide

What are the inputs and the output molecules for respiration?

A. input sugar and oxygen; output carbon dioxide and water

B. input oxygen and water; output sugar and carbon dioxide

C. input carbon dioxide and water;output sugar and oxygen

1.Which of the following would be classified as a product-level activity?

A. Setting up a machine for a batch of a standard product.

B. Operating a cafeteria for employees.

C. Running the Human Resource department.

D. Advertising a product.

2.The plant manager's work is an example of a:

A.Unit-level activity.

B.Batch-level activity.

C.Product-level activity.

D. Facility-level activity.                                                                                                                                                           

3.In activity-based costing, the activity rate for an activity cost pool is computed by dividing the total overhead cost in the activity cost pool by:

A.the direct labor-hours required by the product.

B.the machine-hours required by the product.

C.the total activity for the activity cost pool.

D.the total direct labor-hours for the activity cost pool.