Genetics: Combined Factor V & VIII

Part 1: Describe what happens to the product of the gene that causes the double clotting factor disorder in the ER and the golgi apparatus.Describe what happens to the product of the gene that causes the double clotting factor disorder in the ER and the golgi apparatus.

Part 2: What is the evidence that a mutation in a single gene causes this double deficiency? That is, how does the inheritance pattern differ from what it would be if families inherited each condition independently?

we are talking about the mc68000 microprocessor

a) Explain possible scenarios that would set the V bit of the Status Register in signed number arithmetic operations b) Name 3 Internal Bus and explain their usage and functionality in a microcontroller c) Explain how the displacement is calculated and how the PC gets updated when branching to a subroutine using BSR instruction d) Why do we use MOVEQ or ADDQ instead of MOVE or ADD instruction? (Explain with an example)

V & T Faces, Inc., would like to open a retail store in Miami. The initial investment to purchase the building is $420,000, and an additional $50,000 in working capital is required. Since this store will be operating for many years, the working capital will not be returned in the near future.

V & T Faces expects to remodel the store at the end of 3 years at a cost of $100,000. Annual net cash receipts from daily operations (cash receipts minus cash payments) are expected to be as follows:

The company’s required rate of return is 13 percent. Assume management decided to limit the analysis to 7 years.

1. What is the weakness of using the payback period method to evaluate long-term investments?
2. Assume the manager of the company wanted to live in Miami and intentionally inflated the projected annual cash receipts so that the proposal would be accepted. The proposal would otherwise have been rejected. Explain how the company’s use of a post audit would help to prevent this type of unethical behavior.

Company V earned a net profit margin of 25% on sales of $25 million in its most recently ended fiscal year. Capital investment was $2.5 million and depreciation was $3 million. Investment in working capital is 10% of sales every year. Assume the following:

• Sales, net income, cap ex, depreciation and interest expense are expected to grow 10% every year for the next five years
• After five years sales, net income, cap ex, depreciation and interest expense will decline to a stable growth rate of 4% per year

The tax rate is 36%. Company Z has 1.5 million shares of common stock outstanding. Company Z also has long-term debt paying 10% interest and it is trading at its par value of $30 million.

Calculate the value of the firm and its equity assuming the cost of capital is 15% during years 1-5 and 12% during the stable stage.

In the case of Moskovitz v. Mount Sinai Med. Ctr

If you work for Mt. Sinai Medical Center and you were on their administrative staff trying to establish a finding for whether negligence occurred.

*In doing so, provide an analysis of the potential level of exposure that would support that.

*Include the effect of possibly exposing patient health information (PHI), privacy.

Facts

The evidence supported a finding that the plaintiff's descendent had a very good chance of long-term survival if the tumor was found to be malignant at a time when it was less than one centimeter in size. The evidence supports the fact that the tumor had not grown in size as of May 7, 1987. If doctor Figgie had performed a biopsy prior to this date cancer would not have Metastasized Anne the descendent would have been recovered. Doctor Figgie’s office chart which is the primary reference material in analyzing a physician's conduct it's filled with contradictions and inconsistencies even if doctor Figgie was first informed up the growth on February 23rd, 1987 he still fell below acceptable standards of care because he did not conduct a further investigation until X-rays performed in September 1987 all handwritten entries which appear on or prior to September 24th, 1987 indicating that it bad biopsy was recommended or that the descendent refused further work up to work subsequent changes of the records done to justify feedings condom. The sentence we will, therefore, elect to continue to observe under September 21st, 1987 entry was white and out and the handwritten entry is she does not want exceptional biopsy we will observe what is a subsequent alteration of the records. ID. At 338 the Court of Appeals upheld the finding of liability against Figgie the wrongful death and survival claims the Court of Appeals found that the appellate was not entitled to punitive damages as a matter of law the Court of Appeals revised the judgment of that route as to the award of damages and recommended the case for a new trial only on the issue of compensatory damages.

Issue

Is an intentional alteration or destruction of medical records to avoid liability sufficient to show actual malice? Can punitive damages be awarded regardless of whether the act of altering or destroying records directly causes compensable harm?

Holding

The Ohio Supreme Court held that the evidence regarding the physician's alteration of the patient's records supported an award of punitive damages regardless of whether the alteration causes actual harm.

Reason

The intentional alteration or destruction of medical records to avoid liability for medical neglect negligence is sufficient to show actual malice punitive damage may be awarded regardless of whether the active altering falsifying or destroying records directly causes compensable harm. the jury's award of punitive damages was based on Figgie's alteration or destruction of medical records. The purpose of punitive damages is not to compensate a plaintiff but to punish and deter certain conduct the court warned others to refrain from similar conduct through an award of punitive damages Figgie’s alteration of records exhibited at the total disregard for the law and the rights of MOSKOBITZ and her family had the copy of page 7 of Figgie's office chart had been recovered from the radiation Department records at University Hospital the appellate would have been substantially less likely to succeed in this case. The copy of the chart other records produced by Figgie would have tended 2 exculpate feeding for his medical negligence while placing the blame for his failures on MOSKOVITZ.

1. Adidas is launching a new v-neck “Dynamic Response Short Sleeve Tee” this spring and will be running a promotion in conjunction with the launch. Your buyer has to come to you, the planner to discuss this to make sure their delivery arrives in time for the promotion of all Adidas tops beginning on March 14th. in order to make sure we know when to place the order, our company has been monitoring the Lead Time Variance.

2. (10 points) Calculate The Vendor’s Lead Time Variance from the table below.

You have the following information: Vendor’s Lead Time Forecast 30 days

Vendor’s Shipping History

2.            Vendor’s Lead Time Variance in Days ___________

3.          Vendor’s LTV as a % _____________

4.          To ensure on-time delivery, place order ____________

5.          The earliest date to expect receipt ________________

6.           Place order_______ Earliest Receipt Date __________ Start date of promo___________

G) Explain why it is important to take LTV into consideration when creating planned orders? use all three dates from your timeline above in your answer as well as the variance in days for the first shipment listed in the table. Imagine that you are expecting this to someone who is unfamiliar to this concept. Your answer must be clear

1- Let W1, W2 be two subspaces of a vector space V . Show that
both W1 ∩ W2 and W1 +W2 are subspaces.?and Show that W1 ∪ W2 is a subspace
only when W1 ⊂ W2 or W2 ⊂ W1.
(recall that W1 + W2 = {x + y | x ∈ W1, y ∈ W2}.)

A 10 ohm resistor, 15 mH inductor, and a battery of emf 50.0 V are connected in series through a switch; S. (a) When is the current in the circuit zero? (b) When is the current in the circuit maximum? For both (a) & (b), is it immediately after the switch is closed or long time after the switch is closed? (c) What is the maximum current? (d) What is the time constant of the circuit?