A quote from the article: “Zolgensma is designed to address the genetic root cause of SMA [spinal muscular atrophy] by providing a functional copy of the human SMN gene to halt disease progression through sustained SMN protein expression with a single, one-time IV infusion.”

2. A quote from the article: “AveXis has an exclusive, worldwide license with Nationwide Children's Hospital to both the intravenous and intrathecal delivery of AAV9 gene therapy for the treatment of all types of SMA; has an exclusive, worldwide license from REGENXBIO for any recombinant AAV vector in its intellectual property portfolio for the in vivo gene therapy treatment of SMA in humans; an exclusive, worldwide licensing agreement with Genethon for in vivo delivery of AAV9 vector into the central nervous system for the treatment of SMA; and a non-exclusive, worldwide license agreement with AskBio for the use of its self-complementary DNA technology for the treatment of SMA.”

Based on your knowledge of biotechnology patents, explain why AveXis (a Novartis company) has acquired exclusive licenses to use several different patented methods or materials for their gene therapy system.

ABC Inc, a Canadian retailer which operates more than 1,000 stores in Canada, reported the following balances as at December 31, 2019:

7% Par $100 convertible bonds, issued at par                                          $     250,000

      3,000 call options, each entitled to purchase 1 common share

Cumulative Preferred shares, 36,000 convertible shares outstanding      $     960,000

Common shares, 112,500 shares issued and outstanding                             2,880,000

Contributed surplus on repurchase of common shares                                      31,200

Retained earnings                                                                                         1,032,000

ABC Inc. applies IFRS. The company also informed you details related to the following transactions during 2020:

a]   On February 1, the company declared and distributed a 20% stock dividend for its common shareholders. The shares were being traded in the market at $30.

b]  On March 1, it acquired 18,000 of its own common shares in the market at $30.00 per share and retired them on the same day.

REQUIRED:

1. For transaction [a], Retained earnings decrease by:

1. $576,000
2. 675,000
3. 3,375,000
4. None of the above

2. For transaction [a], the journal entry is:

1. To debit common shares and credit retained earnings
2. To debit retained earnings and credit dividends payable
3. To debit retained earnings and credit common shares
4. None of the above

3. For transaction [b], common shares is decreased by

1. $474,000
2. 540,000
3. 460,800
4. None of the above

4. For transaction [b], retained earnings is decreased by

1. $66,000
2. 31,200
3. 540,000
4. 34,800

5. The journal entry to record transaction [b] is

1. Debit common shares, debit contributed capital, debit retained earnings and credit cash
2. Debit common shares, debit retained earnings and credit cash
3. Debit common shares, credit contributed capital, debit retained earnings and credit cash
4. Debit common shares, credit contributed capital, debit preferred shares, debit retained earnings and credit cash

The Indicator from Planet Money reported that GDP fell by 32.9% in the second quarter of 2020. Wha† value from the GDP calculations are they using to measure the growth rate? Did the economy really shrink by 32.9
% in 3 months? Explain.

1. The article "Where are the mothers?", highlighted the current shortcomings of US policies that support mothers who work outside of the home. Which of the following statements does the author use to support her claim that the US needs better policies to help parents balance paid employment with parenthood?

a. The US is the only developed country in the world that doesn't offer any paid maternity leave

b. A 2014 US study found that 50% of women who work outside of the home took a maternity leave of only 2 weeks or less

c. The Family Medical Leave Act guarantees 12 weeks of paid leave but only to employees who have been with a company for a year or longer

d. All of the above

2. Gender segregation among the types of jobs than men and women tend to perform is called ___________ segregation.

3. Which of the following is true of the wage gap?

a. Women earn 77 cents more than men do for the same work

b. The wage gap is the worst for women of color

c. The wage gap is slowly closing more and more each year

d. All of these are true of the wage gap

4. Which of the following is true of sexual harassment?

a. The #MeToo movement has raised awareness about the prevalence of sexual harassment in the US and worldwide

b. Sexual harassment is a workplace issue and a form of violence

c. Both of the above are true

d. None of the above are true

101)

Suppose that you are valuing a South African diamond producer that sells most of its products in China, records its sales in Chinese RMB, and has most of its employees in China. The company is publicly traded on the South African stock market. Which of the following should be components of your Cost of Equity calculation for this company?

a) Use Chinese government bond yields for the Risk-Free Rate.

b) Use South African government bond yields for the Risk-Free Rate.

c) The Equity Risk Premium should be based on US stock market historical returns, plus a spread to account for the additional risk and potential returns in South Africa (as the company is listed on the South African stock market).

d) The Equity Risk Premium should be based on US stock market historical returns, plus a spread to account for the additional risk and potential returns in China (as the company operates largely in China).

e) Ideally, Levered Beta should be based on comparable diamond producers that operate in China.

f) Ideally, Levered Beta should be based on comparable diamond producers that are headquartered in South Africa but operate largely in China.

102)

Which of the following represent DIFFERENCES in a Levered DCF analysis compared to an Unlevered DCF analysis?

a) You will calculate Terminal Value using an Equity Value-based multiple rather than an Enterprise Value-based one.

b) You will use Levered Beta rather than Unlevered Beta in the Cost of Equity calculations.

c) You will use Cost of Equity instead of WACC for the discount rate.

d) You don’t have to add back non-cash charges in the same way because Levered Free Cash Flow starts with Net Income rather than NOPAT.

e) You will calculate the company’s Implied Equity Value directly from the analysis, rather than calculating the implied Enterprise Value and then backing into the implied Equity Value.

f) When calculating Free Cash Flow, you have to subtract the net interest expense and mandatory debt repayments.

106)

Which of the following events might serve as catalysts if you are drafting a stock pitch for a healthcare company?

a) The launch of new products in any year of the projection period shown in your DCF analysis.

b) The launch of new pipeline drugs in the next 6-12 months.

c) A debt, equity, or convertible issuance within the next year.

d) A key patent expiration in 2-3 years.

e) An annual price increase that the company announces in January each year.

f) US or EU regulators approving a key drug for sale within the next year.

g) An acquisition that is set to close in 18 months.

A graduate student surveyed 220 undergraduate students in a university last week, and found 165 of them prefer F2F classes to online classes. Test the claim that more than 70% of the students at this university prefer F2F classes at the 5% significance level. Include all 5 steps.

Need by 3pm pacific! please help me out !

This semester, there are 259 professors at University A and 128 sent in midterm progress reports. Again, assume the professors at University A are representative of all professors.

(a) Construct a 95% confidence interval for the proportion of all professors who sent in midterm progress reports this semester, and then interpret it. Note: Remember that a confidence interval is made up of three components: pˆ, z, and n. You should have all the information you need to construct the interval.

(b) At CSU San Bernardino, they have 176 professors, of whom 74 sent in midterm progress reports for their students. Is the 95% confidence interval for CSU San Bernardino wider or smaller than the one for University A? Explain answer.

3. The Mathematics & Statistics department at Lancaster University claims that, on average, 25% of students obtain a first class degree. A competitor university is interested in showing that this value is an overestimate. They randomly sample 82 graduates and find that 18 have a host class degree

1. What are the assumptions for conducting a hypothesis test around this data? Are these satisfied?
2. What is your null hypothesis?
3. What is your alternative hypothesis?
4. Calculate the p-value for the hypotheses you proposed in (b) &(c).
5. What is your conclusion when conducting a 95% hypothesis test?
6. Do you agree with the competitor university that the proportion of first-class degrees advertised is an overestimate? State your reasoning.

a)A university planner wants to determine the proportion of spring semester students who will attend summer school. Suppose the university would like a 0.90 probability that the sample proportion is within 0.281 or less of the population proportion.What is the smallest sample size to meet the required precision? (There is no estimation for the sample proportion.)  (Enter an integer number.)

b)A university planner wants to determine the proportion of fall semester students who will attend summer school. She surveys 30 current students discovering that 20 will return for summer school.At 90% confidence, compute the margin of error for the estimation of this proportion.

c)For the t distribution with 14 degrees of freedom, calculate P(T < 2.624)!