A man and his son returned home after playing outside for an hour under strong sunlight. The boy complained to his father that their room is unusually dark.

Explain the boy’s observation using your knowledge of how photoreceptors work.   

Your next patient is Luke, a boy with Down syndrome. Describe how you will prepare for this special needs patient, and identify what techniques you can use to make Luke feel more comfortable and have a positive experience.

Consider the ways that a couple can have three children. Define the following events:

Event M: They have a child of each gender.

Event N: They have at most one boy.

Suppose that they are more likely to have a boy (B) than a girl (G), by a ratio of 11 to 9.

a. Using set notation like I did in the 2-child case (due to time, I didn’t use set notation in the 3-child case), list out the events M, N, and M ∩ N.

b. Carefully calculate the exact values of P(M), P(N), and P(M ∩ N), writing each probability to 4, 5, and 6 decimal places, respectively.

c. Use the definition of independent events to determine if M and N are independent.

A 3 year old boy is brought to the pediatrician with a 102' F fever, cough, a runny nose, and red, watery eyes that have lasted three days. His mother is concerned because the fever is not getting better and her son is in obvious discomfort. The doctor suspects that it is a viral cold and instructs the mother to give an over the counter decongestant, an antihistamine, and ibuprofen for fever.

Two days later the same boy is brought to the Emergency Room. His symptoms have continued and now his face has blotchy, red spots on it. The responding doctor suspects Fifth Disease.

1. What is the etiological agent of Fifth's disease?
2. What symptoms do you think led to that diagnosis?
3. What is the incubation period for the disease?
4. How is it transmitted?
5. What is the treatment?
6. Are there any known complications?
7. What demographic is most likely infected?

Imagine you identified what you believe to be a new, previously-unidentified spe- cies of bacterium. You therefore cultured the bacterium in the lab, purified RNA from the bacteria, made cDNA from the RNA, and obtained its sequence. What next step would you take to confirm whether this is, indeed, a novel species?

Understanding the molecular consequences of CFTR mutations has
significantly contributed to the development of new treatments for
cystic fibrosis.
(a) Discuss how mutations in CFTR lead to cystic fibrosis lung disease
(b) Describe examples of at least three novel treatments that have
been or are being developed to treat cystic fibrosis
(total min 500words)

Write a C program for a library automation which gets the ISBN number, name, author and publication year of the books in the library. The status will be filled by the program as follows: if publication year before 1985 the status is reference else status is available. The information about the books should be stored inside a linked list. The program should have a menu and the user inserts, displays, and deletes the elements from the menu by selecting options. The following data structure should be used. struct list{ char ISBN[ 20 ]; char NAME[ 20 ]; char AUTHOR[ 20 ]; int YEAR; char STATUS[20]; struct list *next; }INFO; The following menu should be used in the program. Press 1. to insert a book Press 2. to display the book list Press 3. to delete a book from list Hint: use strcpy to fill STATUS.

Stamp Printing Corp., a book printer, has provided the following data:

Management believes that the press setup cost is a mixed cost that depends on the number of titles printed. (A specific book that is to be printed is called a "title". Typically, thousands of copies will be printed of each title. Specific steps must be taken to setup the presses for printing each title-for example, changing the printing plates. The costs of these steps are the press setup costs.)

On the basis of the above data, you are required to do the following:

• Estimate the variable cost per title printed and the fixed cost per month using the least-squares regression method.

Massey Machine Shop is considering a four year project to improve its production efficiency. Buying a new machine press for $730,000 is estimated to result in $220,000 in annual pretax cost savings. The press falls in the MACRS five year class, and it will have a salvage value at the end of the project of $89,000. The press also requires an initial investment in spare parts inventory of $26,000, along with an additional $3,000 in inventory for each succeeding year of the project. At the end of the project, all the investment in the inventory will be recaptured. The shop’s tax rate is 40 percent and its discount rate is 9 percent

. What is the operating cash inflows at t=1?

. What is the total cash inflows (operating cash flows plus terminal cash flows) at t=4?

. Compute the NPV of the project.

. Compute the IRR of the project.

. Compute the payback period of the project.