1) Which of the following steps cannot contribute to the regulation of gene expression?

Remodelling of the chromatin

Processing the mRNA.

DNA replication

Initiation of RNA transcription.

The stability of the mRNA.

2) Which of the following statements is true about "housekeeping" genes?

The DNA of housekeeping genes has tighter conformation around the histones than that of inducible genes.

Housekeeping genes are often methylated.

The DNA of housekeeping genes has looser conformation around the histones than that of inducible genes.

Housekeeping genes have unexposed transcription factor (TF) binding elements.

Only a few cells have housekeeping genes.

3) Which of the following statements about the Pre Initiation Complex in eukaryotes is not correct?

The Pre Initiation Complex of proteins assembles at the -10 and -35 sequences.

TF IID assembles at ~ -32 to -24 site along with other transcription factors.

TF IID contains TATA-binding proteins and assembles at the TATA box.

The function of the Pre Initiation Complex in eukaryotes is to place and orient RNA polymerase II so that transcription can be initiated.

RNA polymerase II begins to elongate when it dissociates from the PIC.

4) Which of the following statements about the lac operon is correct?

The Lac promoter is strong so it requires a repressor for negative control.

The Lac promoter is strong because its sequence does not deviate greatly from the consensus sequence.

The Lac promoter is weak because it requires cAMP for transcription.

The Lac promoter is weak because its sequence deviates significantly from the consensus sequence.

Retirement planning.

John and Jane will each contribute to their RRSPs until they are each 71. When they turn 71, CRA rules require them to switch their RRSPs to an annuity and begin receiving payments. John and Jane will receive their first payments on their (respective) 71st birthdays. Each wish to receive a payment of $10,000 per month until they die. If the annuity pays 5% interest compounded monthly, how much must they have saved in their RRSPs if they live until their 81, 91 or 101 birthday?

Sammy Slick works for a company that allows him to contribute up to 10% of his earnings into a tax-deferred savings plan. The company matches a portion of the contributions its employees make based on the organization's financial performance. Although the minimum match is 25% of the employee's contributions and the maximum match is 100%, in most years the company match is about 50%. Sammy is currently 30 years old and makes $35,000. He wants to retire at age 60. He expects his salary to increase in any given year to be at least 2% per year, at most 6%, and most likely 3.5%. The funds contributed by Sammy and his employer are invested in mutual funds. Sammy expects the annual return on his investments to vary according to a normal distribution with a mean of 12.5% and standard deviation of 2%.

a. If Sammy contributes 10% of his income to this plan, how much money could he expect to have at age 60? Round your answer to three decimal places.
$ million

b. Suppose Sammy makes 10% contributions to this plan for eight years, from age 30 to 37, and then stops contributing. How much of his own money would he have invested and how much money could he expect to have at age 60? Round your answers to three decimal places, if necessary.

c. Now suppose Sammy contributes nothing to the plan his first eight years and then contributes 10% for twenty-three years from age 38 to age 60. How much of his own money would he have invested and how much money could he expect to have at age 60? Round your answers to three decimal places, if necessary.

d. What do you learn from Sammy's example?
Invest early

INSTRUCTIONS

Use this form to write and submit your essay to HRTP. Your application will not be considered complete without your essay. The student essay is an important component of the selection process. This essay is read by the review committee and potential preceptors. Please make sure to carefully proofread and review your essay before submitting it to HRTP. Students are encouraged to use personal stories, creativity, as well as critical analysis to inform the review committee about why public health is important to you. In no more than 500 words, answer the following questions:

1. Why are you interested in public health?

2. What will you contribute to HRTP if selected?

3. How will this internship help you in the future?

How do the indicators of social fragmentation described by Eitzen contribute to the kind of political polarization in the United States today that Pew has reported? What role do you think media plays in this fragmentation and polarization? Both of these pieces are from before the 2016 election. What has that election meant for fragmentation and polarization?

contribute to this forum by telling us whether you prefer the "mechanistic" view or the "integral" view? Provide evidence from personal experience or from your culture.

(If you think the metaphysical is real, what does that suggest about the ground of ethics?)

Could you please answer this forum Question of Philosophy in 150 words Thanks :)

In a partnership, a partner can contribute an initial investment, have a drawing account, and have loans to the partnership. Describe the accounting and reporting implications of each of these partner transactions on the formation and reporting of the partnership. Is providing a loan to a partnership on the same level as the initial investment and ongoing profits and losses by a partner? Why or why not?

Discuss the factors that contribute to economic growth. Discuss at least 5 of the factors: 1. Quality and Quantity of a Country's resources 2. Technology 3. Improvements and greater stock of resources 4. Increased productivity 5. Savings and Investment including investment in human capital 6. Infrastructure 7. Research AND Development 8. Protection of Property Rights 9. Free Trade 10. Education

Lane and Hill have decided to form a partnership. Lane is to contribute £150,000 as capital and Hill £20,000. Hill is to work full time in the business and Lane one day a week. Because Hill has no other income, she anticipates making drawings of £1,000 per month from the partnership. Lane expects to make drawings of about £1,000 per quarter. You have been asked to advise the partners on how to share profits in such a way as to compensate each of them for their unequal contributions of capital and labour and withdrawals.

You conduct a QTL mapping experiment to find the genes that contribute to variation in flower color in a plant species. You find that for genetic marker A, the mean flower color is significantly darker in individuals with the A1 allele than for individuals with the A2 allele. What do you conclude? Only one sentence needed for this answer.