Consider the following paragraph.  

Superoxide dismutase is an enzyme that detoxifies a free radical called superoxide.a This radical is responsible for causing injury during reperfusion after a heart attack, and is also thought to play a role in Parkinson’s Disease.b Depending on what organism the protein is found in, it occurs either as a dimer or tetramer of identical subunits.c The subunits are mostly a-helical with some β-sheet near the C-terminus.d A metal binding site for manganese, iron, nickel or copper/zinc is composed of residues from both the N-terminus and the C-terminus.e These residues are: His-26, His-81, Asp-167, His-171.f

Write the letter of the sentence(s) represent primary structure, secondary structure, tertiary structure, and quaternary structure in the above paragraph? You may or may not use all the letters. Explain your choices.

Primary structure =

Secondary structure =

Tertiary structure =

Quaternary structure =

Place the following steps of TRANSLATION in the correct order for EUKARYOTES.

The ribosome reaches a stop codon. A release factor binds and causes the release of the new polypeptide, along with the mRNA. The ribosome dissociates.

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The ribosome moves exactly 3 nucleotides toward the 3' end of the mRNA.

The small ribosomal subunit binds the mRNA near the 5' end and begins to search for the start codon.

A charged tRNA with a matching anticodon binds the mRNA codon in the A site.

The initiator tRNA binds to the small ribosomal subunit.

The ribosome catalyzes the formation of a peptide bond between the amino acids held by the tRNA in the P site and the new amino acid on the charged tRNA in the A site. This tRNA ends up holding the whole chain of amino acids.

The small ribosomal subunit uses rRNA to bind to the Kozak sequence, which places the initiator tRNA on the start codon and in the P site.

The large ribosomal subunit joins the small subunit, ending the Initiation phase.

Use R studio to answer the following questions

Temperatures are extremely variable in sections of the Colorado River near the Glen Canyon Dam.  Researchers measure temperature in two locations (1 and 2) with samples of size n₁ = 10 and n₂ = 16, and calculate variances of s₁² = 20 °C ²and s₂² = 15 °C ².

1. Construct a 98% confidence interval for the ratio s₁²/s₂². (Hint: copy this data into a .csv file and read into R, or read in as vectors.)
2. Interpret this interval.
3. Test the hypothesis that the two variances are equal at a = 0.10. Be sure to list (i) your hypotheses, (ii) test statistic, (iii) decision, and (iv) conclusion.

Three weeks after returning from a camping trip to New Mexico, a 25-year-old female developed a fever and severe muscle aches. She also had a dry cough, headaches, nausea, and vomiting. Four days later the symptoms became progressively worse as fluid began to accumulate in her lungs and she went to the emergency room. Microbiological tests are various bacterial pathogens were negative. The patient’s symptoms worsened and she experienced cardiac arrest and died. An epidemiologist was called in to investigate the person’s death (1 pt each).

a. Based on this person’s travel history and clinical signs, what disease (be specific) did she likely have?      

b. What type of sample should be run from this patient?      

c. What would the epidemiologist be looking for at and near the campsite?      

d. What other common pathogen is quite possibly the culprit (hint: unrelated to patient history)?

Seth and Elsa Robbins are trying to decide where to go on a vacation trip. Seth had been interested in going to the Florida Keys, but they rejected that based on reports from friends that it wasn't that interesting. They briefly considered a trip to Aruba, but Elsa didn't like the idea of leaving the country. Two very expensive resorts in Palm Beach were also considered, but rejected because both Seth and Elsa were afraid they would feel out of place at such "fancy" accommodations. Finally, they settle on a moderate priced motel near Disney World and Epcot Center, where they have previously enjoyed relaxing visits.

Are there other influences you would add? How do these psychological variables and social/cultural influences impact the marketing strategy used to reach these people? Which items—psychological variables or social influences—have the most influence over consumer behavior and thus are more important for the marketing strategy planner?

Weatherwise is a magazine published by the American Meteorological Society. One issue gives a rating system used to classify Nor'easter storms that frequently hit New England and can cause much damage near the ocean. A severe storm has an average peak wave height of μ = 16.4 feet for waves hitting the shore. Suppose that a Nor'easter is in progress at the severe storm class rating. Peak wave heights are usually measured from land (using binoculars) off fixed cement piers. Suppose that a reading of 34 waves showed an average wave height of x = 17.7 feet. Previous studies of severe storms indicate that σ = 3.8 feet. Does this information suggest that the storm is (perhaps temporarily) increasing above the severe rating? Use α = 0.01. Solve the problem using the critical region method of testing (i.e., traditional method). (Round your answers to two decimal places.) test statistic = critical value =

Now that you're taking a finance class, I was hoping you could settle a disagreement that your father and I are having. We are considering buying stock in General Electric (GE). We agree on what the dividends will be in the near future and how risky the company is, but I liked to hold stock in our portfolio for just a couple of years and your dad likes to hold for 10 years or more. Based on what you've been learning about valuing financial assets, do you think we should be able to agree on a fair price for the stock given how we can't agree on how long to hold the stock? That is, should our intended holding period affect what we should be willing to pay? I hope to hear from you soon! Also, when are you coming to see us? It has been too long!

Need help Answering this question.

1) What is the shortest possible length of an mRNA molecule that corresponds to a polypeptide 10 amino acids long? For your answer just give me the number. E.g., "12" or "120." (Ignore the 5' cap and poly-A tail.)

2) How can the deletion of one nucleotide result in a longer polypeptide being made? Write out 2 examples of mRNA sequence (before and after the mutation) and its corresponding amino acid sequence (before and after the mutation) to show how this could happen.

3)In the metabolic pathway above, paraoxon is the most toxic compound. What change would likely lead to the greatest build-up of paraoxon in the body?

Group of answer choices

a) decrease in the amount of diethylphosphate and p-nitrophenol in the body.

b) nonsense mutation near the beginning of the gene that codes for cytochrome P450.

c) silent mutation in the gene that codes for paraoxonase.  

d) severe change in the shape of the active site of paraoxonase.

Let's discuss joints and the mechanics of the skeletal system. Pick a joint and identify the bones that are involved in that joint.

• The joint I picked is the ball and socket joint.
• What might be the lumps/bumps (named correctly) that are associated with that joint to act as the surface for the joint to move, as well as points for muscle attachment that may cause that joint to move?

Example: Knee joint is a hinge joint and is made up of the femur and the tibia. The patella (a sesamoid bone) plays a role by helping with muscle movement but doesn't actually form part of the knee joint. The fibula is located in the same area but doesn't form part of the knee joint. The joint surfaces are the condyles of the femur superiorly resting on the condyles of the tibia. Both the femur and the tibia have epicondyles which are for muscle attachments that help in movement of the knee joint. The tibia also has the tibial tuberosity which is for muscle attachment near the knee. The range of motion of the knee is flexion and extension.

1. CMA Ltd currently has an enterprise value​ (that is, present value of future free cash flows) of $400 million and $100 million in excess cash. The firm has 10 million shares outstanding and no debt. Suppose CMA uses its excess cash to repurchase shares. In the near future there news is scheduled to come out that will change​ AMC's enterprise value to either $600 million or $200 million.

1. Suppose CMA management expects good news to come out. If management’s goal is to maximize price per share, what would be optimal for CMA to do – purchase shares before the news or after the news? Explain, provide necessary computations

2. Now answer question a) assuming that CMA management expects bad news to come out.

3. Suppose CMA announces stock repurchase program before the news release date. What would you expect the announcement to have on the stock price? Why?