Delsing Canning Company is considering an expansion of its facilities. Its current income statement is as follows:

The company is currently financed with 50 percent debt and 50 percent equity (common stock, par value of $10). In order to expand the facilities, Mr. Delsing estimates a need for $2.8 million in additional financing. His investment banker has laid out three plans for him to consider:

1. Sell $2.8 million of debt at 10 percent.
2. Sell $2.8 million of common stock at $20 per share.
3. Sell $1.40 million of debt at 9 percent and $1.40 million of common stock at $25 per share.

Variable costs are expected to stay at 50 percent of sales, while fixed expenses will increase to $2,380,000 per year. Delsing is not sure how much this expansion will add to sales, but he estimates that sales will rise by $1 million per year for the next five years.
Delsing is interested in a thorough analysis of his expansion plans and methods of financing.He would like you to analyze the following:

a. The break-even point for operating expenses before and after expansion (in sales dollars). (Enter your answers in dollars not in millions, i.e, $1,234,567.)
  

b. The degree of operating leverage before and after expansion. Assume sales of $5.8 million before expansion and $6.8 million after expansion. Use the formula: DOL = (S − TVC) / (S − TVC − FC). (Round your answers to 2 decimal places.)
  

c-1. The degree of financial leverage before expansion. (Round your answer to 2 decimal places.)
  

c-2. The degree of financial leverage for all three methods after expansion. Assume sales of $6.8 million for this question. (Round your answers to 2 decimal places.)
  

d. Compute EPS under all three methods of financing the expansion at $6.8 million in sales (first year) and $10.8 million in sales (last year). (Round your answers to 2 decimal places.)
  

Scenario
Tim is a 40-year-old sustainable farmer who works daily in his farm fields. After a long day getting his fields ready for planting, he comes in and falls into bed, exhausted.

The next morning as he’s taking a shower, he feels a small lump on the back of his leg, behind his knee. Since he can’t really see it, he dries off and asks his wife to look at it. Initially she thinks it looks like a scab, but upon closer inspection she notices it has legs!

She runs for the tweezers and pulls the tick off, and then notices that he actually has three more ticks embedded higher up on the back of his thigh.

Signs and Symptoms
Tim had been bitten by ticks and treated for Lyme disease before, so he decided to wait to see if a rash developed. After checking the spots daily for a week and not seeing anything other than a small, red, raised area around a few of the tick bite sites, he stopped worrying.

About 10 days later, Tim developed a fever and started to have bouts of extreme fatigue that were not alleviated by resting or sleep. The fatigue got to the point that he couldn’t get out of bed. When he started to act disoriented and confused, his wife drove him to the hospital.

Testing
Blood was drawn and sent to the hematology, clinical chemistry, and microbiology laboratories.

Question 1: What symptoms would indicate that Tim’s disease could be due to an infection involving the central nervous system?

Question 2: What is the significance of these findings in the peripheral blood smear?

While his attending physician struggled to figure out what was wrong, Tim became unresponsive. Additional samples were sent to serology to assess his exposure to viruses known to cause encephalitis, specifically West Nile Virus (WNV), Eastern Equine Encephalitis Virus (EEE), and Powassen Virus (POW), as well as tests for other tick-borne diseases common to his area.

Serology Test Results:
WNV, EEE, and POW—negative
Lyme disease serology—equivocal
Babesia microti and B. duncanii —negative
Ehrlichia monocytogenes—negative
Anaplasma phagocytophilium—positive

Question 3: Discuss the results of the collective laboratory tests— are the serology test results consistent with what the hematologist observed in the stained blood smear?

Question 4: Do you think Tim has Lyme disease?

Diagnosis
Tim was diagnosed with anaplasmosis, caused by Anaplasma phagocytophilium.

Question 5: Is it necessary for the hospital to report Tim’s case of anaplasmosis to the CDC for disease surveillance? Why?

Over the next two months, seven other people with Tim’s symptoms were admitted to the same regional hospital. Six tested positive for anaplasmosis and were successfully treated, but the seventh person died before a diagnosis could be reached. She subsequently was found to be positive for Anaplasma. In the previous year, there had been no cases of anaplasmosis diagnosed at the hospital.

Question 6: What epidemiological term(s) apply to this scenario?

Treatment
Once it was affirmed that Tim was infected with Anaplasma, treatment with IV ceftriaxone was immediately started via a peripherally inserted central catheter (PICC). After 2 days on the antibiotic he was alert but still overwhelmingly fatigued. After a week he was feeling well enough to be released from the hospital, but visited an infusion center daily for the rest of the month. He was also given oral doxycycline.

By the end of the year, a total of 26 cases of anaplasmosis were diagnosed at the hospital, which was the only medical facility in Tim’s county of residence. The county population (from census data) that year was 6,982 people.

Question 7: What is the incidence of anaplasmosis in Tim’s county?

Question 8: Is this also the prevalence of anaplasmosis in Tim’s county? Why?

Use SPSS to get the appropriate output. Along with providing the SPSS output, use the 5 steps of hypothesis testing to analyze the results by using the p-value approach.

4. Workers went through a training program to help them in the packaging of items needed for the purchaser to assemble a toy. The number of defective packages returned per month is recorded for each employee doing the packaging. Below are the before and after number of defects per month per employee. Test to see if the mean difference in defects has lowered after the employees went through the training program. Test at the 0.01 level of significance.

Linearly polarized light that is oriented along the x-axis and has intensity I0 is incident on a linear polarizer (LP1) with transmission axis oriented at an angle θ1=15° clockwise with respect to the x axis. The light then passes through a second linear polarizer (LP2) with transmission axis oriented at an angle θ2 = 45° counterclockwise relative to the x axis as shown before passing through a quarter wave plate. The fast axis of the quarter wave plate is aligned with the y-axis

What is the intensity of the light after the second linear polarizer (LP2) but before the quarter wave plate?

What is the polarization after the light passes through the quarter wave plate?

Keeping the linear polarizers and quarter wave plate exactly the same, the incident light is now changed to be unpolarized as shown below. What is the intensity of light measured after the quarter wave plate(IQWP)?

1 (met) 2 (asp)    3 (gly) 4 (glu)    5 (trp)

The following pentapeptide MET-ASP-GLY-GLU-TRP is initially treated with cyanogen Bromide, and subsequently treated with Chymotrypsin. Based on this information, answer the following: Identify the carboxyl and amino terminus of the pentapeptide before treatment and indicate if terminal side chain groups are ionizable? If applicable, indicate which reagents result in chemical cleavage or enzymatic cleavage. Biochemical approaches can be used to determine the differences in the peptide before and after treatment. Indicate two biochemical approaches and what is being analyzed using this approach. Indicate any free amino acids and/or peptide fragments that result after cyanogen bromide treatment. If applicable, indicate any free amino acids and/or peptide fragment sequences that result after cyanogen bromide treatment and subsequent treatment with chymotrypsin.

2-2.  In the 1950’s Matthew Meselson and Franklin Stahl did an experiment in which they took bacteria that had grown for many generations in medium containing the stable nitrogen isotope 15N, and transferred them into medium containing only the 14N isotope of nitrogen.  They purified DNA from these bacteria at time zero (before transfer to 14N) and after 1 and 2 rounds of DNA replication in 14N medium.

1. When they analyzed the density of DNA molecules at time zero (before bacteria had been in the 14N medium), what did they observe?

2. When they analyzed the density of DNA molecules after one round of DNA replication, what did they observe?

3. When they analyzed the density of DNA molecules after two rounds of DNA replication, what did they observe?

4. What was the major conclusion from the Meselson-Stahl experiment?

SAT coaching: A sample of 10 students took a class designed to improve their SAT math scores. Following are their scores before and after the class. Can you conclude that the mean increase in scores differs from 15 points? Let μ1 represent the mean score after the class and μd=μ1-μ2. Use the α=0.10 level and the P-value method with the table.

1. State the appropriate null and alternate hypotheses.
2. Compute the test statistic. Round the answer to at least three decimal places.
3. Estimate the P-value. Identify the form of the interval based on the Critical Values for the Student's t Distribution Table.

d. Determine whether to reject H0

e. State a conclusion.

7. The University Skydiving Club has asked you to plan a stunt for an air show. In this stunt, two skydivers will step out of opposite sides of a stationary hotair balloon 1500 meters above the ground. The second skydiver will leave the balloon 20 seconds after the first skydiver but you want them both to land on the ground at the same time. The show is planned for a day with no wind so assume that all motion isvertical. To get a rough idea of the situation, assume that a skydiver will fall with a constant acceleration of 9.80 m/s2before the parachute opens. As soon as the parachute is opened, the skydiver falls with a constant velocity of 3.2 m/s. If the first skydiver waits 3 seconds after stepping out of the balloon before opening her parachute, how long must the second skydiver wait after leaving the balloon before opening his parachute?

Dr. Zhivàgo Diagnostics Corp.'s income statement for 20X1 is as follows:
  

   
a. Compute the profit margin for 20X1. (Input the profit margin as a percent rounded to 2 decimal places.)
  

Profit margin _____%

b. Assume that in 20X2, sales increase by 10 percent and cost of goods sold increases by 20 percent. The firm is able to keep all other expenses the same. Assume a tax rate of 30 percent on income before taxes. What is income after taxes and the profit margin for 20X2? (Input the profit margin as a percent rounded to 2 decimal places.)

20X2

income after taxes____

profit margin ______%

Eight breasts of 7− to 8−week old broiler chickens weighing 0.9 to 1.2 kilograms were taken at random from a poultry-processing plant. The concentration of sarcoplasmic protein (mg N/g tissue) in the breast muscles of these specimens were measured before and after they were irradiate with 10 kGy. The data are presented below:

a) (7 points) At the 2.5 percent level, is there a significant decrease in the true mean sarcoplasmic protein after irradiation? State the assumption(s) required for the test.

b) (3 points) Construct a 95% confidence interval for the μdμd.