1. What is the importance or advantage of studying "Drug Repurposing" for a better understanding of the human disease drug discovery process?
2. Provide two examples of human diseases where researchers used this concept or research strategy. What is the cellular mechanism of disease, or signaling pathway targeted by these researchers? Please cite two sources using PubMed!
3. What are the potential disadvantages or challenges of drug repurposing?
In: Biology
In: Psychology
1. Use the neoclassical theory of distribution to predict the impact on the real wage and the real rental
price of capital of each of the following events:
a. A wave of immigration increases the labor force.
b. An earthquake destroys some of the capital stock.
c. A technological advance improves the production function.
d. High inflation doubles the prices of all factors and outputs in the economy.
2. If a 10 percent increase in both capital and labor causes output to increase by less than 10 percent, the production function is said to exhibit decreasing returns to scale. If it causes output to increase by more than 10 percent, the production function is said to exhibit increasing returns to scale.
Why might a production function exhibit decreasing or increasing returns to scale?
(This problem requires the use of calculus.)
Consider a Cobb–Douglas production function with three inputs. K is capital (the number of machines), L is labor (the number of workers), and H is human capital (the number of college degrees among the workers).
The production function is
Y =5 K 1/3 L1/3 H 1/3.
a. Derive an expression for the marginal product of labor. How does an increase in the amount of human capital affect the marginal product of labor?
b. Derive an expression for the marginal product of human capital. How does an increase in the amount of humancapital affect the marginal product of human capital?
c. What is the income share paid to labor?
What is the income share paid to human capital?
In the national income accounts of this economy, what share of total income do you think workers would appear to receive?
(Hint: Consider where the return to human capital shows up.)
d. An unskilled worker earns the marginal product of labor, whereas a skilled worker earns the marginal product of labor plus the marginal product of human capital.
Using your answers to parts (a) and (b), find the ratio of the skilled wage to the unskilled wage. How does an increase in
the amount of human capital affect this ratio? Explain.
3. Suppose that an increase in consumer confidence raises consumers’ expectations about their future income and thus increases the amount they want to consume today. This might be interpreted as an upward shift in the consumption
function. How does this shift affect investment and the interest rate?
4. Suppose that the government increases taxes and government purchases by equal amounts. What
happens to the interest rate and investment in response to this balanced-budget change?
Explain how your answer depends on the marginal propensity to consume.
5.Suppose that consumption depends on the interest rate. How, if at all, does this alter the conclusions reached in the chapter about the impact of an increase in government purchases on investment, consumption, national saving, and the
interest rate?
In: Economics
A newspaper infographic titled "Social Media Jeopardizing Your Job?" summarized data from a survey of 1,845 recruiters and human resource professionals. The infographic indicated that 52% of the people surveyed had reconsidered a job candidate based on his or her social media profile. Assume that the sample is representative of the population of recruiters and human resource professionals in the United States.
(a)
Use the given information to estimate the proportion of recruiters and human resource professionals who have reconsidered a job candidate based on his or her social media profile using a 95% confidence interval. (Use a table or technology. Round your answers to three decimal places.
( . , )
Give an interpreation of the interval context
We are 95% confident that the mean number of recruiters and human
resource professionals who have reconsidered a job candidate based
on his or her social media profile falls within this interval.
We are 95% confident that the true proportion of recruiters and human resource professionals who have reconsidered a job candidate based on his or her social media profile falls within this interval.
There is a 95% chance that the true proportion of recruiters and human resource professionals who have reconsidered a job candidate based on his or her social media profile falls within this interval.
We are 95% confident that the true proportion of recruiters and human resource professionals who have reconsidered a job candidate based on his or her social media profile falls directly in the middle of this interval.
There is a 95% chance that the true proportion of recruiters and human resource professionals who have reconsidered a job candidate based on his or her social media profile falls directly in the middle of this interval.Give an interpretation of the interval in context.
Give an interpretation of the confidence level of 95%.
Of all possible random samples, 95% would result in an interval that includes the actual value of the population proportion.
Of all possible random samples, 95% would result in an interval that lies below the actual value of the population proportion.
Of all possible random samples, 5% would result in an interval that lies above the actual value of the population proportion.
Of all possible random samples, 95% would result in an interval that is centered at the actual value of the population proportion.
Of all possible random samples, 5% would result in an interval that includes the actual value of the population proportion.
(b)
Would a 90% confidence interval be wider or narrower than the 95% confidence interval from part (a)?
wider
narrower
In: Statistics and Probability
b) Ethane gas at 1 bar and 25 oC is compressed adiabatically to 55 bar in a steady-state flow process for which W = 10 J mol-1. Assume ethane is ideal gas at its initial state and the residual enthalpy of the gas at its final state is - 3270 J/mol, and its heat capacity is constant (CP = 4.5 R), the temperature of ethane at the final state, i.e., after compression, is
i. 403.3 oC; ii. 403.3 K; iii. 130.1 oC; iv. 130.1 K v. Other
c) Air enters the opening of a jet engine of an airplane flying at Mach 2.2. We want to convert the kinetic energy of the incoming airflow to pressure before the air is introduced to the entrance of a compressor, which is to compress the air stream to a pressure that is slightly higher than that in the combustion chamber. To increase the efficiency of such a conversion of energy, we should design the engine entrance channel as a diffuser so that
i) dP/dx > 0 ii) du/dx < 0; iii) dA/dx < 0; iv) I, ii, and iii ; v) None
Answer BOTH and EXPLAIN WHY
In: Other
Biology: Topic - Molecules of Life
1. How many bonds can a carbon atom have?
2. Explain (Understand) that functional groups provide molecules with new chemical characteristics.
3. Define metabolism, catabolism, anabolism
4. Define polymer, define monomer
5. List the four macromolecules of life (polymers) and the monomers that each are made up of
6. Define enzyme
7. Define carbohydrate
8. Differentiate between a monosaccharide, disaccharide, and a polysaccharide (define).
9. Compare structure and functions of starch, cellulose, glycogen, and chitin.
In: Nursing
Determine the activation energy (kJ) from the following table.
Temperature (K) 427 417 409 407 399
k (s-1) 0.00108 0.000410 0.000208 0.00016 0.0000763
| A.25 | |
| B.77 | |
| C.89 | |
| D.134 |
You have discovered a new enzyme and want to characterize its function. The reaction catalyzed is 20 times more rapid at 25° C than at 4° C. Calculate the activation energy (kJ) for the reaction.
| A.24 | |
| B.41 | |
| C.83 | |
| D.100 |
In: Chemistry
In: Nursing
The Enzyme Lactase experiment design
Material required:
Skim milk, lactase drops, test tubes, glucose test strips, eye dropper, mixing spoon, graduated cylinder
|
Step: |
Why this step is important: |
If you actually conducted this experiment, what safety issues would you need to identify?
If you actually conducted this experiment, what appropriate precautions would you take to ensure that you performed the experiment safely?
If you actually conducted this experiment, what results would you expect to see?
In: Biology
Describe what occurs after the toothpick is dropped into each bottle . ( each bottle is filled with 1/3 of hydrogen peroxide and must shake each bottle for 15 minutes with each item in it then light a tooth pick on fire blow it out and drop it into the bottle with the cap on but not twisted) what hapepns ?
Bottle 1- Nothing added________
Bottle 2- Raw meat added________
Bottle 3- Cooked meat added____________
Talk about the difference between the behavior of the three bottles. Be sure to comment on the possible effect of cooking enzyme activity.
In: Chemistry