Consider the data in the following table:

Use the above information to answer the following questions. Round your answers to four decimal places (i.e. 0.0105).

1. Estimate the average return for stock A.

2. Estimate the average return for stock B.

3. Estimate the volatility of stock A.

4.Estimate the volatility of stock B.

5 .Estimate the correlation between the two stocks.

In August 2004, Bonnie Martin bought a house for $391,000. She put 20% down and financed the rest with a thirty-year loan at the then-current rate of 5 3 4 %. In 2007, the real estate market crashed. In June 2009, she had to sell her house. The best she could get was $235,000. Was this enough to pay off the loan?I got no. If so, how much did she profit? If not, how much did she have to pay out of pocket to pay off the loan? (Round your answer to the nearest cent.) I got 76150.53 which is incorrect

Amstat News (December 2004) lists median salaries for associate professors of statistics at research institutions and at liberal arts and other institutions in the United States. Assume a sample of 200 associate professors from research institutions having an average salary of $70,750 per year with a standard deviation of $6000. Assume also a sample of 200 associate professors from other types of institutions having an average salary of $65,200 with a standard deviation of $5000. Test the hypothesis that the mean salary for associate professors in research institutions is $2000 higher than for those in other institutions. Use a 0.01 level of significance.

confused for what the alternative hypothesis is...

On 1/1/2004, an insurance company invested $1,000,000 developing an annuity product that will produce returns of $150,000 per year for the next 10 years (assume at the end of each year) following which the product will have to be abandoned.

The net present value of the project is $100,000.

At the end of 5 years, the opportunity cost of capital for the project decreased by 3 percentage points (or 3%), with the rest of the project remaining unchanged.

The insurance company recalculates the net present value as the present value of the remaining cash flows at the new opportunity cost of capital.

Find the value of the project on 1/1/2009.

a.

485,000

b.

535,000

c.

585,000

d.

635,000

e.

685,000

Clinical Trial

Between 2004 and 2007, the National Institutes of Health conducted a STEP vaccine clinical trial—Phase IIB "test-ofconcept" study.

The STEP study is the name of a clinical trial to test an experimental human immunodeficiency virus (HIV) vaccine. The STEP study enrolled 3,000 participants at sites in Australia, Brazil, Canada, the Dominican Republic, Haiti, Jamaica, Peru, Puerto Rico, and the United States. The study was designed to test an HIV vaccine, which aimed to stimulate production of immune system T-cells that can kill HIV-infected cells.

Based on its first evaluation of vaccine efficacy, the findings showed there were 24 cases of HIV infection among the 741 volunteers who received at least one dose of the investigational vaccine compared with 21 cases of HIV infection among the 762 volunteers who were vaccinated with the placebo. In volunteers who received at least two vaccinations, there were 19 cases of HIV infection among the 672 volunteers who received the investigational vaccine and 11 instances of HIV infection among the 691 volunteers who received placebo. The study investigators of the vaccine trials have decided to cease immunizations and are contacting study volunteers to inform them of the developments.

Reference:

National Institutes of Health (2007). National Institute of Allergy and Infectious Diseases: Immunizations are discontinued in two HIV vaccine trials. Retrieved from National Institute of Allergy and Infectious Diseases Pages/step_statement.aspx.

Using the South University Online Library or the Internet, research further on the STEP study, the STEP vaccine clinical trials, and their parameters.

Based on your research, understanding, and above information, answer the following questions:

Prior to beginning this study, how would you have described the risks and benefits of the study to participants?

What are the ethical issues surrounding this study at the beginning and when the decision was made to terminate the study?

Yasser Arafat, former chairman of the Palestine Liberation Organization (PLO), died in November 2004, after a brief illness. Not surprisingly, his death aroused considerable suspicion, particularly given that his symptoms were somewhat consistent with acute radiation poisoning. In November 2012, samples of tissue were obtained from his corpse and tested—by three independent research groups—for evidence of poisoning by a highly radioactive isotope of Polonium. The results, though far from conclusive, suggest that Arafat died as a result of polonium-210 poisoning.

Polonium-210 is a short-lived isotope in the uranium decay series. Together with thallium-206, polonium-210 is a penultimate daughter product in the 238U → 206Pb decay series. Polonium-210 occurs in trace amounts in uranium ores; annually, about 100 grams of 210Po is produced (synthetically) in reactors. 210Po decays to 206Pb via alpha emission with a radiogenic half-life of 138 days. The ejected alpha particle has an energy of 5.3 MeV. The biological half-life of 210Po is about 40 days, i.e. it takes your body about 40 days to excrete half the amount of 210Po originally ingested. For the purposes of this class, the fatal internal dose (D50) of radiation from an ingested alpha emitter like 210Po is approximately 0.25 Joule of energy absorbed per kilogram of body mass. (Note: The D50 notation indicates the dosage that proves fatal for half of a population; D50 ~ 0.25 J/kg for 210Po.) For those interested in dosage units, 0.25 J/kg = 0.25 Gy = 5 Sv = D50 for an alpha emitter absorbed internally (Q factor of 20).

1 (20 pts.): Assuming access to a ‘fresh’ polonium source, i.e. straight from the reactor, would one microgram (1 μg) of ingested 210Po kill Arafat? (FYI: 1 μg of 210Po is equivalent to approximately one grain of silt.) If yes, then approximately what time interval was required to absorb a fatal dose? Note: There is typically a lag time of days to weeks between the time at which a fatal dose is absorbed and the actual time of death. Arafat died about two weeks after the onset of symptoms. Discuss very briefly some of the complications we might expect in analyzing Arafat’s corpse for signs of 210Po poisoning in 2012.

1) clear and concise explanations of your reasoning and 2) careful calculations using scientific notation. The answer should be presented clearly and logically.

In 2004, Congress allocated over $20 billion to fight illegal drugs. About 60 percent of the funds was directed at reducing the supply of drugs through domestic law enforcement and interdiction. Some critics of this approach argue that supply-side approaches to reduce the drug supply actually helped drug producers.

• Demonstrate graphically the effect of supply-side measures on the market for illegal drugs.
• Explain how these measures affect drug producers. (Hint: Consider the elasticity of demand).
• Demonstrate the effect of demand-side measures such as treatment and prevention on the market for illegal drugs.
• How does the shift in demand affect the profitability of producers?

Clinical Trial Between 2004 and 2007, the National Institutes of Health conducted a STEP vaccine clinical trial—Phase IIB "test-ofconcept" study. The STEP study is the name of a clinical trial to test an experimental human immunodeficiency virus (HIV) vaccine. The STEP study enrolled 3,000 participants at sites in Australia, Brazil, Canada, the Dominican Republic, Haiti, Jamaica, Peru, Puerto Rico, and the United States. The study was designed to test an HIV vaccine, which aimed to stimulate production of immune system T-cells that can kill HIV-infected cells. Based on its first evaluation of vaccine efficacy, the findings showed there were 24 cases of HIV infection among the 741 volunteers who received at least one dose of the investigational vaccine compared with 21 cases of HIV infection among the 762 volunteers who were vaccinated with the placebo. In volunteers who received at least two vaccinations, there were 19 cases of HIV infection among the 672 volunteers who received the investigational vaccine and 11 instances of HIV infection among the 691 volunteers who received placebo. The study investigators of the vaccine trials have decided to cease immunizations and are contacting study volunteers to inform them of the developments.

Reference: National Institutes of Health (2007). National Institute of Allergy and Infectious Diseases: Immunizations are discontinued in two HIV vaccine trials. Retrieved from National Institute of Allergy and Infectious Diseases Pages/step_statement.aspx.

Using the South University Online Library or the Internet, research further on the STEP study, the STEP vaccine clinical trials, and their parameters. Based on your research, understanding, and above information, answer the following questions:

Prior to beginning this study, how would you have described the risks and benefits of the study to participants?

What are the ethical issues surrounding this study at the beginning and when the decision was made to terminate the study?

1. Fictitious data—real data is available and would be interesting]

In the period 1980-2004, 8.7% of named Atlantic tropical storms were measured as “strong” hurricanes (Category 3 or higher at some point in their active “lifetime”).

As a test of one predicted effect of climate change, we want to see if this proportion has remained the same for the period 2005-2017. Assume there were 183 named Atlantic tropical storms in this period. Assume also that the 8.7% is (at least very close to) the true long-term proportion of these storms [which is the correct approach for this test].

1. What are the mean proportion and the standard deviation in that proportion for the sample of 183 storms?
2. Can we use the normal approximation for the proportion?
3. How likely would it be to find more than 10% “strong” hurricanes in the 2005-2017 period? How about 12.5%? If 12.5% of the 2005-2017 storms were strong, would you classify this as very unusual?

Question # 1

Rothenberg et al. (2004) investigated the effectiveness of using the Hologic Sahara Sonometer, a portable device that measures bone mineral density (BMD) in the ankle, in predicting a fracture. They used a Hologic estimated bone mineral density value of

.57 as a cutoff. The results yielded the following data:

a. Compute the Sensitivity of the test. (6 points)

b. Compute the Specificity of the test. (6 points)

c. Compute the Positive Predictive Value (6 points)

Question # 2

According to the most recent Davenport student profile, 28% of students are male. Given a sample of 15 students:

a. Find the probability that none are male. (6 points)

b. Find the probability that 10 are male. (6 points)

c. Find the probability that at least six are male. (6 points)