If you want to reproduce the shuttling experiment as performed during week 3. you will need to purchase Cycloheximide (CHX) from one of three potential suppliers. CHX has a molar mass of 281.35 g/mol and can be dissolved in DMSO, water, or EtOH but with different solubilities. You will need to use CHX at a final working concentration of 17 μg/mL in a 150 mm dish with a total media volume of 14 mL.

Determine how much of the stock solution purchased from each company you would need (in μL) to add to the media in the 150 mm dish to obtain the final working concentration of CHX. Give your answers in μL using the scientific notation.

a. Company A supplies CHX dissolved in DMSO at 100 mg/ mL:

Volume needed in μL

b. Company A supplies CHX dissolved in water in 2% (w/v) solution

Volume needed in μL:

c. Company A supplies CHX dissolved in EtOH at 50 mM

Volume needed in μL:

A partial list of the costs for Wisconsin and Minnesota Railroad, a short hauler of freight, follows. Classify each cost as either indirect or direct. For purposes of classifying each cost, use the train as the cost object.

I need a recommendation on which stock i should recommend to investors based on companies’ financial reports, ratio and 10-k report. (A)Southwest Airline (B) American Airline=

All the ratio For Southwest Airlines:

Return on Equity (ROE): 2017=37.0% and 2016= 28.4%

Return on Assets (ROA): 2017=14.4% and 2016= 10.1%   

Net profit margin (PM); 2017=16.5% and 2016=11.0%

PPE Turn Over(PPET); 2017=1.19 and 2016=1.25

Total Asset Turnover (AT): 2017=0.87 and 2016=0.92

Gross Profit Margin(GPM); 2017= 100% and 2016 100%   

Currnet Ratio: 2017=0.69 and 2016=0.65

Quick Ratio: 2017=0.57 and 2016=0.56

Acoount Receivable Turnover: 2017=32.00 and 2016= 37.40

Times interest earned: 2017=30.83 and 2016=30.82

liability to Equity Ratio: 2017=1.41 and 2016=1.76   

Financial Leverage: 2017=2.56 and 2016=2.82

All the ratio For American Airlines:

Return on Equity (ROE): 2017=14.1% and 2016= 24.9%

Return on Assets (ROA): 2017=3.3% and 2016= 5.1%

Net profit margin (PM); 2017=4.6% and 2016=6.9%

PPE Turn Over(PPET); 2017=1.30 and 2016=1.38

Total Asset Turnover (AT): 2017=0.71 and 2016=0.74

Gross Profit Margin(GPM); 2017= 100% and 2016 100%

Currnet Ratio: 2017=1.25 and 2016=1.25

Quick Ratio: 2017=0.50 and 2016=0.63

Acoount Receivable Turnover: 2017=15.2 and 2016= 14.5

Times interest earned: 2017=4.08 and 2016=5.85

liability to Equity Ratio: 2017=3.11and 2016=3.59

Financial Leverage: 2017=4.34 and 2016=4.86

1. The theory of atherosclerosis (hardening and narrowing of the arteries) emphasizes the role of inflammation in the vascular walls. Because ibuprofen is known to possess a wide range of anti-inflammatory actions, it was hypothesized that it might help in the prevention of atherosclerotic lesion development. Both a low-cholesterol and a high-cholesterol diet were used, as the extent of atherosclerosis is also affected by diet. Sixteen New Zealand rabbits served as subjects in the experiment and, after three months, the percentage of the surface covered by atherosclerotic plaques in a region of the aorta was evaluated. Although ibuprofen did suppress the expression of a gene thought to be related to atherosclerosis, it was not shown to have an effect on the extent of fat-induced atherosclerotic lesions.
   1. a) What are the individuals in this experiment?
   2. b) What is the response variable in this experiment?
   3. c) List the explanatory variable(s) in this experiment.
   4. d) How many treatments are there in this experiment? Complete an appropriate table that shows the treatment set up.
   5. e) Using the specific information given in the scenario and the treatments you identified in part (d), sketch a diagram to show a completely randomized design for this experiment (but don’t do the randomization).
   6. f) Should we consider any level of blinding in this experiment?

Question 1 :

1. A computer program is said to learn from experience E with respect to some class of tasks T and performance measure P, if its performance at tasks in T, as measured by P, improves with experience

For a voice recognition learning problem determine the possible:

1. task T
2. performance measure P
3. and training experience E

Question 2 :

2. Explain what is the curse of dimensionality? What is the relation between machine learning problems and the curse of dimensionality?

Question 3 :

3. The following training dataset is “reading email dataset”.

This dataset has four features as follows: author, thread, length, and where to read the mail. According to the features the algorithm has to predict the user’s action whether to read or skip the mail.

Use Naïve Bayes classifier to predict the user’s action (skips or reads) when the author of the mail is known, the thread of the mail is follow up, the length of the mail is short, and where to read the email is home.

1. (35 points) Write a Python code to implement a naïve Bayesian classifier to predict the user’s action (skips or reads) when the author of the mail is known, the thread of the mail is follow up, the length of the mail is short, and where to read the email is home. (Do not use Scikit-Learn)
2. (35 points) Use Scikit-Learn to predict the user’s action (skips or reads) when the author of the mail is known, the thread of the mail is follow up, the length of the mail is short, and where to read the email is home.

Hint in authors feature you can use 0, 1 instead of unknown and known. In thread feature you can use 0, 1 instead of follow up and new. In length feature you can use 0, 1 instead of short and long. In where to read feature you can use 0, 1 instead of home, work. In the target you can use 0 instead of skips and 1 instead of reads.

Problem 1. Using the INVOICE table structure shown in table below do the following:

1. Write the relational schema, draw its dependency diagram, and identify all dependencies, including all partial and transitive dependencies. You can assume that the table does not contain repeating groups and that an invoice number references more than one product. (Hint:This table uses a composite primary key.)
2. Remove all partial dependencies, write the relational schema, and draw the new dependency diagrams. Identify the normal forms for each table structure you created.
3. Remove all transitive dependencies, write the relational schema, and draw the new dependency diagrams. Also identify the normal forms for each table structure you created.
4. Draw the Crow’s Foot ERD.

Problem 2. Use the dependency diagram shown below to work the following problems.

Initial Dependency Diagram for Problem

Figure 1

5. Break up the dependency diagram shown in Figure 1 to create two new dependency diagrams: one in 3NF and one in 2NF.
6. Modify the dependency diagrams you created in part a to produce a set of dependency diagrams that are in 3NF. (Hint:One of your dependency diagrams should be in 3NF but not in BCNF.)
7. Modify the dependency diagrams you created in Part b to produce a collection of dependency diagrams that are in 3NF and BCNF.

Answer the following questions about the ventilation-perfusion (V/Q) ratio.  

A patient has pneumonia in the left lower lobe of the lung. The pneumonia has caused bronchoconstriction, pulmonary edema, and alveolar collapse (atelectasis) resulting in a significant decrease in ventilation (V). Describe the V-Q alteration, the body’s response to this V-Q mismatch, and the clinical consequences.

A patient has severe chronic obstructive pulmonary disease which results in a lung-wide decrease in alveolar ventilation. Describe the V-Q alteration, the body’s response to this V-Q mismatch, and the clinical consequences.

A patient has a blood clot in the lungs (pulmonary embolus) resulting in decreased alveolar perfusion (Q). Describe the V-Q alteration, the body’s response to this V-Q mismatch, and the clinical consequences.

What was the significance of the 1944 Avery-MacLeod-McCarty experiment? How are the discoveries of that experiment a significant contribution to the field of biotechnology?

Explain Thomas's famous "Unconscious violinist " thought experiment. what is this thought experiment supposed to show about abortion?

Subject: Introduction Statistics

The Star Tribune Newspaper posted a survey online and asked people to click on the survey to indicate how they feel about the current mayor of Minneapolis. Why does the author of our text think this is not the best way to gather good data on how the city feels about the mayor? (2pts)